The health of our mitochondria determines the amount of adenosine triphosphate (ATP) they can produce from the calories we eat and oxygen we consume. Without robust mitochondria, cells cannot do as much work as they’re capable of and we need them to do so we can stay healthy.
Mitochondria are the parts of our cells that produce energy. Antibodies against mitochondria are produced in some autoimmune conditions. The detection of mitochondrial antibodies is useful in the evaluation of a number of conditions.
Various subtypes of these antibodies have been associated with primary biliary cirrhosis, syphilis, pseudosyphilis, and isoniazid-induced hepatitis. A titer of above 50 IU/ml of M2 mitochondrial antibodies suggests primary biliary cirrhosis even in the absence of symptoms and the presence of normal alkaline phosphatase levels.